LeiteAP, et al. (2012). Use and effectiveness of papain in the wound healingprocess: A systematic review [Abstract]. An acute toxicity test (median lethal dose) in adult male Wistar rats demonstrated that papaya juice (from the ripe fruit) was not lethal, with no signs of toxicity observed in rats receiving up to and including doses as high as 1,500 mg/kg after oral administration. Thus, papaya juice is considered nontoxic. Mehdipour 2006

Caricol® is a tasty, convenient all-natural fruit puree for anyone wishing to support more regular bowel movements. It is made from the pulp of tree-ripened papaya, and prepared to the original recipe used by the Lotus Buddhist Monastery on Big Island in Hawaii. Papaya fruit has a long history of traditional use in both Traditional Chinese Medicine (TCM) and Ayurvedic Medicine for helping to speed up digestive transit time. It is naturally high in papain, a potent proteolytic enzyme which helps to break down proteins, and studies have shown it to have soothing effects on the stomach and digestive tract. Caricol® is delicious and easy to consume and is suitable for practically everyone, from infants (6m+), pregnant and breastfeeding women, right through to the elderly. Internim aktom određeno je da će se osobni podaci u digitalnom ili papirnatom obliku čuvati 11 (jedanaest) godina od dana prestanka obveza između voditelja obrade i Ispitanika, nakon čega će biti trajno uništeni.Avoid use. Papaya may be unsafe depending on the part of the plant being used and dose administered. Interactions kada se traži unos (novih) osobnih podataka koji nisu javno dostupni, a nisu uneseni u sustav temeljem druge pravne osnove Ukoliko Zahtjev šaljete putem e-pošte isti će biti obrađen isključivo ako je poslan sa Vaše postojeće e-pošte koju imamo evidentiranu u našem informacijskom sustavu. Podaci koje ćete dati na ovom obrascu koristiti će se isključivo u svrhe identificiranja osobnih podataka koje tražite i odgovora na Vaš zahtjev. Rješavanje nesporazuma ili dodatna pitanja Voditelj obrade će odgovoriti na zahtjev i/ili prigovor u roku od 30 dana od njegova zaprimanja. Taj se rok može prema potrebi produžiti za dodatna dva mjeseca (od dana njegova zaprimanja) uzimajući u obzir složenost i broj zahtjeva.

To consider interactions with gastric fluid, Caricol ®-Gastro, oat I and oat II were mixed with simulated gastric fluid (SGF) in the ratio 1:1. SGF was prepared according to the United States Pharmacopoeia [ 49]. Briefly, 2.06 g NaCl were dissolved in 1000 g MQ-water and the pH was adjusted to pH 1.2. The viscoelastic properties were determined at 37 °C using the same test setup as the pure formulations. The results of both measurements were compared. Abortifacient properties have been reported in female rats, Bodhanker 1974, Garg 1971 while decreases in sperm motility and count have been reported in male rats Chinoy 1985, Das 1980, Fansworth 1982, Lohiya 1994, Lohiya 2006, Manivannan 2009, Pathak 2000 and rabbits. Pathak 2001Voditelj obrade će o povredi osobnih podataka izvijestiti nadzorno tijelo bez nepotrebnog odgađanja i to, ako je izvedivo, najkasnije 72 sata nakon saznanja o toj povredi osobnih podataka, osim ako Voditelj obrade može dokazati, u skladu s načelom odgovornosti, da povreda osobnih podataka vjerojatno neće prouzročiti rizik za prava i slobode pojedinaca. Ako se takvo obavješćivanje ne može postići u roku od 72 sata, obavijest bi trebala biti popraćena razlozima kašnjenja, a informacije se mogu pružiti u fazama bez nepotrebnog daljnjeg odgađanja. Čuvanje osobnih podataka Diuretic activity is associated with the aqueous extracts of C. papaya. Adult male Sprague-Dawley rats were given an oral dose of 10 mg/kg of C. papaya root extracts. The demonstrated increased urine output ( P<0.01) was similar to effects with hydrochlorothiazide 10 mg/kg. Sripanidkulchai 2001 Various topical applications of papaya have been used for wound healing, particularly in developing countries. Burns 1997, Hewitt 2002, Sieggreen 1997, Singhal 2001, Starley 1999 There are very little data available to make specific recommendations regarding systemic doses of papaya. AdebiyiA, et al. (2002). Papaya (Carica papaya) consumption is unsafe in pregnancy:Fact or fable? Scientific evaluation of a common belief in some parts of Asiausing a rat model [Abstract]. DOI: In this study the participants were volunteers, with chronic (prevailing) indigestions and dysfunctions in the gastrointestinal tract. During the trial the intake of the substance of intent and placebo was 20 ml daily for 40 days. The endpoints were the frequency of 22 symptoms recorded before and after the documented intake recorded by questionnaire.

extractul de ovăz conține β-Glucani ce are efecte pozitive asupra metabolismului și avenantramide care ajută la inhibarea eliberării de mediatori ai inflamației; Various topical applications of papaya have been used for wound healing, particularly in developing countries. There are very little data available to make specific recommendations regarding systemic doses of papaya. Pravo na pritužbu nadzornom tijelu: ako ne postupimo prema Vašem zahtjevu radi ostvarivanja Vaših prava kao ispitanika u roku od 30 dana od dana primitka Vašeg zahtjeva, o tome ćemo Vas obavijestiti pisanim putem. Ako smatrate da smo našim postupkom povrijedili Vaša prava kao ispitanika, imate pravo podnijeti pritužbu Agenciji za zaštitu osobnih podataka, na adresi: Martićeva ulica 14, 10000 Zagreb, web: http://azop.hr , telefon: +385 01 4609 000. APĂ; PIURE DIN FRUCTE DE PAPAYA* (CARICA PAPAYA) - 39,4 %; FAINA DE OVAZ* (AVENA SATIVA) - 6,25 %; SUC CONCENTRAT DIN FRUCTE DE MAR (MALUS DOMESTICA). Questionsand answers about FDA’s enforcement action regarding unapproved topical drugproducts containing papain. (2015).Papaya, a tropical plant believed to have originated in southern Mexico and Central America, is now cultivated in tropical and subtropical regions worldwide for its edible ripe fruit; its juice is a popular beverage, and its young leaves and shoots are cooked as vegetables. Duke 1983, Hewitt 2002, Monti 2004 The fruits are a source of flavoring used in candies, jellies, preserves, and ice cream. Shallow cuts on the surface of fully grown but unripe fruits cause the exudation of a milky sap or latex that is collected, dried, and termed "crude papain." Foster 1999 Papain, a proteolytic enzyme, has a wealth of industrial uses, including milk-clotting (rennet) and protein-digesting properties. Nearly 80% of American beer is treated with papain, which digests the precipitable protein fragments and causes the beer to remain clear upon cooling. Duke 1983 Commercially, papain is most commonly used in meat tenderizers and chewing gums. Duke 1983, Foster 1999 Cosmetically, papain is used in some dentifrices, shampoos, and facial creams. Duke 1983

In the early 1980s, chymopapain was approved for intradiscal injection in patients with documented herniated lumbar intervertebral discs who had not responded to conservative therapy. Chymopapain 1982 This procedure is effective Javid 1980, Javid 1996, but remains controversial, particularly regarding safety of the administration of the enzyme. Diagnostic 1989 Chemistry Nakon prestanka svrhe obrade osobnih podataka, ovisno o pojedinim pravnim temeljima obrade, dokumentacija koja je do tada bila čuvana u papirnatom obliku komisijski će se uništiti, a digitalni podaci će se anonimizirati ili u potpunosti brisati. Papaya seed extract may exert potentially toxic effects on mammalian vascular smooth muscle. Benzyl isothiocyanate, the chief bioactive ingredient in seeds, irreversibly inhibits the contraction of dog carotid artery. Wilson 2002 Papaya extract, when present in high concentrations, was cytotoxic by increasing the membrane permeability to calcium. Wilson 2002 References Disclaimer Ispitanik daje svoju privolu jasnom potvrdnom radnjom kojom izražava dobrovoljan, poseban, informiran i nedvosmislen pristanak na obradu osobnih podataka koji se odnose na njega, poput pisane izjave, uključujući elektronsku. Ukoliko Ispitanik nije suglasan s odlukom Društva u vezi prigovora ili postupanja po njegovom zahtjevu, može podnijeti prigovor Agenciji za zaštitu osobnih podataka kao nadležnom tijelu.Doua plicuri zilnic, cate un plic cu 15 minute inaintea mesei sau cate un plic intre mesele principale. Le mode de vie moderne peut déséquilibrer votre digestion. Ce que vous mangez mais aussi comment et quand prenez nos repas influence votre digestion. Plus encore, certains facteurs extérieurs (comme des situations stressantes ou une trop forte sédentarité peuvent affecter votre digestion, aux même titre que les polluants environnementaux. One study used 20 mL of an elixir containing air-dried papaya seeds in honey (prepared by mixing 500 g of air-dried, machine-blended seeds with honey, for a total preparation volume of 1,000 mL [ie, 0.2 g of dried C. papaya seeds per milliliter]) to treat helminthiasis in children. Priprava Caricola poteka po patentiranem proizvodnem procesu, ki za 7-krat izboljša učinek papaje na prebavo in za 4-krat poveča njeno encimsko učinkovitost.